Semi Prep HPLC Column, HPS Silica, 5um, 120A. 10mm ID x 150mm Length. Cogent Brand. 1 EA.
Additional Info:
75001-SP150 Cogent HPS Silica™ Semi‑Prep HPLC Column is packed with high‑purity, unmodified silica, delivering consistent and reproducible performance for normal phase purification of polar and hydrophilic compounds.
Because the stationary phase is not chemically modified, it provides strong surface interactions with polar analytes, making it ideal for semi‑preparative purification of fats, lipids, and other hydrophilic compounds.
This proprietary HPS Silica™ has been widely adopted as a premium-value alternative to commonly used silica phases such as Inertsil® and Luna®, providing dependable selectivity and long-term reproducibility across laboratories.
The 5 µm particle size is well suited for semi‑prep workflows, allowing:
Higher flow rates
Lower system backpressure compared to smaller particles
Reliable performance under repeated purification cycles
150 mm Length – Enhanced Resolution for Purification
The 150 mm length provides increased resolving power for more challenging separations.
Higher resolution than 50 mm and 100 mm formats
Improved separation of closely related compounds
Increased peak capacity for complex mixtures
✅ Recommended for purification workflows requiring higher resolution and improved separation quality
10 mm ID – Semi‑Preparative Scale
Designed for semi‑preparative purification workflows
Increased sample loading capacity vs analytical columns
Suitable for analytical‑to‑prep scale‑up
Compatible with fraction collection systems
✅ Recommended for mid‑scale purification and process development
Flow Rate & System Requirements (10 mm ID, 5 µm)
⚠️ Requires semi‑preparative HPLC system capability
Typical flow rate range: ~4 – 12 mL/min
Low-to-moderate backpressure
Designed for higher flow purification
Compatible with preparative detectors and fraction collectors
✅ Important: A specialized HPLC system is required for columns of this size
Why Choose HPS Silica™ for Semi‑Prep
High‑Purity Unmodified Silica
Strong retention for polar compounds
Ideal for normal phase purification
USP L3 Compatibility
Suitable for compendial methods
Reliable alternative to traditional silica columns
Proven Performance
Widely used across HPLC labs
Consistent, reproducible results
Performance Advantages
Low Backpressure (5 µm Particles)
Enables higher flow rates
Compatible with prep-scale systems
Fast Equilibration
Reduces purification cycle times
Strong Polar Retention
Ideal for lipids and hydrophilic compounds
Typical Applications
Semi‑preparative purification of fats and lipids
Normal phase separations
Polar compound isolation
Method scale‑up from analytical HPLC
Pharmaceutical and chemical purification workflows
Important Usage Notes
Designed for normal phase chromatography conditions
Use appropriate non‑polar mobile phases
Requires semi‑preparative HPLC system capability
Ensure proper equilibration for reproducible results
Made‑to‑Order Columns & Pricing Information
This is a custom, made‑to‑order column.
Columns are manufactured specifically to order
Orders cannot be canceled once placed
Custom columns are non‑returnable